Presentation: PBS, pH 7.4, 500 mM sodium chloride, 15 mM sodium azide, 40% glycerol.
Target Species: Human
Host Species: Mouse
Specificity: Recognizes human vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). Species Crossreactivity: feline, canine, goat, bovine and to a lesser extent with equine. Binds nearly as well to native vitronectin as to denatured. Is a potent inhibitor of integrin-mediated cell adhesion to vitronectin and a moderate inhibitor of PAI-1 binding.