Anti-POLL / DNA Polymerase Lambda Antibody (C-Terminus) IHC-plus LS-B2284

Product Description

Presentation: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

Target Species: Human

Host Species: Goat

Specificity: Human POLL. It has been brought to our attention that this product may crossreact with Pol beta (NP_002681), an evolutionarilly related polymerase with a predicted size of 39 kDa. The overall % of identity is not very high (about 32% in the core) but considering only the peptide that we used as immunogen the two share the sequence YREP**R** at the C-terminus. Further the protein structures appear to be very similar in this region.

Reactivity: Rabbit, Mouse, Bovine, Rat, Hamster, Pig, Bat, Human, Monkey

Usage: ELISA (1:32000), IHC-P (5 g/ml)

Synonyms: POLL, DNA polymerase beta-2, DNA polymerase beta-N, DNA polymerase lambda, DNA polymerase kappa, Pol beta2, BETAN, Pol Lambda, POLKAPPA

Concentration: 0.5 mg/ml

Volume:

Immunogen: Synthetic peptide C-LGLPYREPAERDW from the C-terminus of human POLL (NP_037406.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Panda, Rabbit, Pig (100%); Dog, Opossum, Turkey, Chicken (92%); Xenopus, Zebrafish, Sea anemone (85%).