Anti-MAdCAM-1 Antibody (clone 314G8, Low Endotoxin) IHC-plus LS-B3316

$495.00

SKU:

LS-B3316

Product Description

Presentation: PBS, pH 7.4.

Target Species: Human

Host Species: Mouse

Specificity: Recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1), a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone Reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7

Reactivity: Human

Usage: ELISA, Flo (1:10 - 1:100), IHC-P (10 g/ml), WB

Synonyms: MADCAM1, HMAdCAM-1, MACAM1, MAdCAM-1

Concentration: 1 mg/ml

Volume:

Immunogen: Recombinant soluble MAdCAM-1-fc fusion protein.