Anti-HLA-E Antibody (clone MEM-E/06) IHC-plus LS-B3729

$495.00

SKU:

LS-B3729

Product Description

Presentation: Tris buffered saline (TBS), 15 mM sodium azide, approx., pH 8.0. Sourced in Ascites.

Target Species: Human

Host Species: Mouse

Specificity: Recognized native surface-expressed HLA-E, but not denatured heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that the antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that the antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7

Reactivity: Human, Primate

Usage: Flo, IHC-P (10 g/ml), IP

Synonyms: HLA-E, EA2.1, HLAE, MHC HLA-E alpha-2.1, MHC HLA-E alpha-1, EA1.2, HLA-6.2, MHC class I antigen E, QA1

Concentration: 1 mg/ml

Volume:

Immunogen: Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide.