Anti-H2AFX / H2AX Antibody (C-Terminus) IHC-plus LS-B3282

$495.00

SKU:

LS-B3282

Product Description

Presentation: Tris-citrate/phosphate, 0.09% sodium azide.

Target Species: Human

Host Species: Rabbit

Specificity: Specific for human histone H2AX. H2AX comprises approximately 2-25% of the histone H2A pool in mammalian cells. The extended C-terminal tail of H2AX contains a serine (Ser139) embedded in an conserved SQE motif, which is rapidly phosphorylated at sites of double strand breaks and stalled replication forks. Phosphorylated H2AX may serve to recruit other repair proteins to the site of DNA damage. H2AX has been implicated in both homologous recombination and nonhomologous end joining DNA repair pathways

Reactivity: Human

Usage: IF (1:400 - 1:800), IHC-P (2.5 g/ml), WB

Synonyms: H2AFX, H2AX, Histone H2A.x, H2A.X, H2A histone family, member X, H2AX histone

Concentration: 1 mg/ml

Volume:

Immunogen: Synthetic peptide corresponding to a region within the C-terminus of human H2AX.