Presentation: 20 mM Tris/HCl, 15 mM sodium azide, approx., pH 7.4.
Target Species: Human
Host Species: Mouse
Specificity: Reacts with CD95 (Fas/APO-1), a 46 kD single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.