Presentation: PBS, 15 mM sodium azide, approx., pH 7.4.
Target Species: Human
Host Species: Mouse
Specificity: Reacts with a protein determinant of CD45RB, a 180-240 kD single chain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB is expressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. The MEM-143 is therefore not neuraminidase sensitive like most other anti-CD45RB antibodies (including standard antibody MEM-55). The reactivity of the antibody MEM-143 can be blocked by a peptide including amino acids 79-88.