Anti-Basic Cytokeratin AE3 Antibody (clone AE3) IHC-plus LS-B5557

$495.00

SKU:

LS-B5557

Product Description

Presentation: 0.01M PBS containing 0.1% Sodium azide and 1% BSA. Sourced in Ascites.

Target Species: Human

Host Species: Mouse

Specificity: This antibody has shown to recognize most of the basic (type II) keratins. Each epithelium contains at least one basic keratin. In this way AE-3 is broadly reactive with almost all epithelial and there neoplasms. This antibody together with AE-1 has been used for studying the immuno-localization of epidermal keratins, tissue distribution and epithelia development. AE-1 and AE-3 have also been used extensively, individually or mixed, for distinguishing carcinoma from non-carcinoma. The antibody is cross-reactive with keratins of rabbit, mouse, rat, bovine and chicken. Within immunoblots AE-1 detects distinct MWs of 52 kD, 54 kD, 56 kD, 58 kD, 59 kD, 64 kD, and 65-67 kD with all Ips lower then 6.0. These MWs are believed to correspond with respectively keratin 8, 7, 6, 5, 4, 3 and 1 & 2.

Reactivity: Human

Usage: IHC-Fr, IHC-P (1:100), WB (1:100)

Synonyms: ,

Concentration: 1 mg/ml

Volume:

Immunogen: Human epidermal cells.