Anti-CCR5 Antibody IHC-plus LS-B275

Product Description

Presentation: PBS

Target Species: Human

Host Species: Rabbit

Specificity: This antibody demonstrates 2D7-like reactivity. The synthetic peptide used was made to the epitope binding site of the monoclonal antibody 2D7-2SK. The sequence EWQKEGLVTLWLGGGGSC is a combination of the two distal ends of extracellular loop 2 (ECL-2) on the human CCR5 sequence. The binding site is conformation dependent and will only detect the protein if the disulfide bridge between extracellular loop 1 and 2 is intact. It will not detect the protein in its reduced form.

Reactivity: Human, Primate

Usage: ELISA (1 g/ml), Flo (25 g/ml), IHC-P (5 g/ml)

Synonyms: CCR5, C-C chemokine receptor 5, CD195 antigen, CD195, C-C CKR-5, Chemokine c-c motif receptor 5, Chemr13, CMKBR5, CKR5, Cc chemokine receptor 5, CCCKR5, CCR-5, Ccr5 receptor, Chemokine receptor CCR5, HIV-1 fusion coreceptor, IDDM22, C-C chemokine receptor type 5, CC-CKR-5, CKR-5

Concentration: 0.5 mg/ml

Volume: 100 µl

Immunogen: A synthetic peptide demonstrating a high affinity towards the monoclonal CCR5 2D7 (see reference 2). This peptide is known as the 2D7-2SK peptide and consists of the following residues: EWQKEGLVTLWLGGGGSC