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Glucagon IHC Antibody

$258.00
SKU:
IW-MA1047
Quantity:

 

Product Description

Description

Glucagon is a member of a multigene family that includes secretin. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. the human glucagon gene is approximately 9.4 kb long and contains 6 exons and 5 introns, and assigned to 2q36-2q37.

 

Catalog Number

 

IW-MA1047

Quantity

 

9 ml

Host

 

Mouse

 

Clone

 

IMD-7

 

Isotype

 

Mouse IgG1

 

Immunogen

 

Polymerized porcine glucagon.

Purity

 

Purified by the goat anti-mouse IgG affinity chromatography.

Conjugate

 

Unconjugated

 

Species Reactivity

 

Human, rat. Not tested in other species.

Positive Control

 

Pancreas.

 

Cellular Localization

 

Cytoplasmic

 

Form

 

Ready to use solution in PBS with stabilizer and 0.01% sodium azide. No further dilution needed. Serum blocking step should be omitted.

 

Storage

 

Store at 2-8 °C. Do not freeze.

 

Applications

 

IHC-P: Formalin fixed paraffin embedded tissue sections. Heat mediated antigen retrieval is required. IHC-Tek Epitope Retrieval Solution (IW-1100) is recommended.

IHC-Fr: Not tested.

ICC: Not tested.

 

Limitations

 

This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.

 

Precautions

 

Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.

 

References

 

1. Schroeder, W. T.; Lopez, L. C.; Harper, M. E.; Saunders, G. F. : Localization of the human glucagon gene (GCG) to chromosome segment 2q36-37. Cytogenet. Cell Genet. 38: 76-79, 1984.

2. White, J. W.; Saunders, G. F. : Structure of the human glucagon gene. Nucleic Acids Res. 14: 4719-4730, 1986.

 

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