Description |
Collagen IV is comprised of a third chain(alpha-3) together with the |
Catalog Number
|
IW-MA1030 |
Quantity
|
9 ml |
Host
|
Mouse
|
Clone
|
Col-30
|
Isotype
|
Mouse IgG1
|
Immunogen
|
Human collagen type IV
|
Purity
|
Purified by the goat anti-mouse IgG affinity chromatography. |
Conjugate
|
Unconjugated
|
Species Reactivity
|
Human, rat. Not tested in other species. |
Positive Control
|
Human mammary cancer, kidney, skin.
|
Cellular Localization
|
Cytoplasmic
|
Form
|
Ready to use solution in PBS with stabilizer and 0.01% sodium azide. No further dilution needed. Serum blocking step should be omitted.
|
Storage
|
Store at 2-8 °C. Do not freeze.
|
Applications
|
IHC-P: Formalin fixed paraffin embedded tissue sections. IHC-Fr: Formalin or acetone fixed frozen sections. ICC: Not tested.
|
Limitations
|
This product is intended for Research Use Only. Interpretation of the test results is solely the responsibility of the user.
|
Precautions
|
Users should follow general laboratory precautions when handling this product. Wear personal protective equipment to avoid contact with skin and eyes.
|
References
|
1. Kalluri, R.; Gattone, V. H., II; Noelken, M. E.; Hudson, B. G. : The alpha-3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Proc. Nat. Acad. Sci. 91: 6201-6205, 1994. 2. Badenas, C.; Praga, M.; Tazon, B.; Heidet, L.; Arrondel, C.; Armengol, A.; Andres, A.; Morales. E.; Camacho, J. A.; Lens, X.; Davila, S.; Mila, M.; Antignac, C.; Darnell, A.; Torra, R. : Mutations in the COL4A4 and COL4A3 genes cause familial benign hematuria. J. Am. Soc. Nephrol. 13: 1248-1254, 2002.
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